Gene interactions and pathways from curated databases and text-mining

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BAX — HUNK

Text-mined interactions from Literome

Sundararajan et al., J Virol 2001 (Adenoviridae Infections) : TNF-alpha and truncated Bid induced Bax-Bax cross linking, indicative of oligomerization, and E1B 19K expression during infection inhibited this TNF-alpha mediated Bax oligomerization
Sundararajan et al., J Biol Chem 2001 : TNF-alpha induces E1B 19K-Bax interaction and inhibits Bax oligomerization ... E1B 19K was constitutively in a complex with Bak, and blocked the Bak-Bax interaction and oligomerization of both
Henry et al., Oncogene 2002 (Cell Transformation, Viral) : When p53 dependent apoptosis was blocked by E1B 19K expression, E1B 19K bound Bak, and the Bax-Bak interaction was inhibited
Cross et al., Cell Death Differ 2008 : In this defined system we show that changes in mitochondrial ultrastructure, characteristic of cells undergoing apoptosis, precede Bax activation and are not blocked by E1B19K and BHRF1
Han et al., Genes Dev 1996 : bax mRNA and protein levels were p53-inducible with kinetics identical to that of p21/Waf-1/Cip-1, and E1B 19K and Bcl-2 expression did not affect Bax or p21/Waf-1/Cip-1 accumulation