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BCR — TCF7
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Schuster et al., Blood 2003
:
The
effects of
Bcr-Abl on C/EBP
transcription-factor regulation and neutrophilic differentiation are reversed by the Abl kinase inhibitor imatinib mesylate
Christian et al., J Biol Chem 2003
:
Preventing Rap activation also increased the ability of the
BCR to
stimulate Akt dependent phosphorylation of the FKHR
transcription factor on negative regulatory sites and decreased the levels of p27Kip1, a pro-apoptotic factor whose transcription is enhanced by FKHR
Bilancio et al., Blood 2006
:
p110delta activity is indispensable for
BCR induced DNA synthesis and phosphorylation of Akt/protein kinase B (PKB), forkhead
transcription factor/forkhead box O3a (FOXO3a), and p70 S6 kinase (p70 S6K), with modest effects on the phosphorylation of glycogen synthase kinase 3 alpha/beta ( GSK3alpha/beta ) and extracellular signal regulated kinase ( Erk )
Stein et al., Oncogene 2011
:
Previously we have shown that the
transcription factor nuclear factor-kappa B ( NF-?B ) is
activated by
BCR-ABL expression and is required for BCR-ABL mediated cellular transformation