Bougatef et al., Blood 2009
(Neoplasms, Experimental) :
In addition, EMMPRIN up-regulated the expression of VEGFR-2 without an effect on VEGFR-1 ... This increase in VEGFR-2 was responsible for the observed EMMPRIN stimulation of the migratory and tube formation capacity of endothelial cells
Bougatef et al., PloS one 2010
(Disease Progression...) :
EMMPRIN regulation of VEGFR-2 was mediated through the over-expression of HIF-2alpha and its translocation to the nucleus where it forms heterodimers with HIF-1beta