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HIF1A — TLR2

Text-mined interactions from Literome

Regueira et al., Liver Int 2009 : The aim of this study was to evaluate the effects of cobalt chloride ( CoCl ( 2 ), a hypoxia mimicking agent ), tumour necrosis factor-alpha (TNF-alpha) and toll-like receptor (TLR) -2 , -3 and -4 agonists on HIF-1 alpha accumulation, and further on HIF-1 alpha mediated modulation of mitochondrial respiration in cultured human hepatocytes
Spirig et al., PloS one 2010 : In this study, we show that exogenous as well as endogenous inflammatory stimuli for TLR4 and TLR2 induce the expression of HIF-1alpha in human monocyte derived DC under normoxic conditions ... In addition, we could show that TLR stimulation resulted in an increase of HIF-1alpha controlled VEGF secretion