Mabuchi et al., Transfus Apher Sci 2004
(Cardiovascular Diseases...) :
Premature coronary heart disease (CHD) can result from high LDL cholesterol levels even in the absence of any other risk factors
Horton et al., J Lipid Res 2009
:
The identification and characterization of proprotein convertase subtilisin-like/kexin type 9 ( PCSK9 ) have provided new insights into LDL metabolism and the causal role of LDL in coronary heart disease (CHD) Vega et al., J Lipid Res 1984
(Coronary Disease...) :
Levels of LDL-apoB followed a similar pattern : CHD-NLP ( 88 +/- 25 mg/dl ), CAD-NLP ( 83 +/- 25 mg/dl ), CHD-HTG ( 94 +/- 30 mg/dl ), CAD-HTG ( 89 +/- 25 mg/dl ), hypertensive controls ( 89 +/- 24 mg/dl ), middle aged controls ( 80 +/- 25 mg/dl ) and younger controls ( 58 +/- 14 mg/dl )