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IL13 — IL1RN

Text-mined interactions from Literome

Mühlberg et al., J Clin Endocrinol Metab 2000 (Graves Disease) : Recent data have indicated that orbital fibroblasts ( OF ) can be stimulated to produce marked quantities of interleukin-1 receptor antagonist ( IL-1RA ), a powerful inhibitor of the proinflammatory activities of interleukin-1 in the orbital tissues in Graves ' ophthalmopathy ( GO )
Kovár et al., Parasitol Res 2002 : ELISA ( protein level ) and RNAse protection assay ( mRNA level ) showed that SGE enhanced interleukin (IL)-1alpha, IL-1beta, IL-1Ra , IL-6, and IL-12p40 cytokines, whereas production of IL-2, IL-5, IL-10, and IL-13 was decreased
Cominelli et al., Gastroenterology 1992 (Colitis) : Recombinant interleukin-1 receptor antagonist blocks the proinflammatory activity of endogenous interleukin-1 in rabbit immune colitis
Burger et al., J Clin Invest 1995 : The inhibitory activity of human interleukin-1 receptor antagonist is enhanced by type II interleukin-1 soluble receptor and hindered by type I interleukin-1 soluble receptor
Yanagawa et al., Am J Respir Cell Mol Biol 1995 : Contrasting effect of interleukin-13 on interleukin-1 receptor antagonist and proinflammatory cytokine production by human alveolar macrophages ... We investigated the effect of interleukin-13 (IL-13) on production of IL-1 receptor antagonist (IL-1ra) and proinflammatory cytokines by human alveolar macrophages ( AM ) ... AM spontaneously produced IL-1ra , and this production was significantly augmented by IL-13 ... In contrast, IL-13 caused a small but reproducible increase in LPS induced IL-1ra production
Deleuran et al., Cytokine 1995 : IL-13 induced a 3-fold increase of the IL-1ra secretion which was inhibited by rIFN-gamma
Vannier et al., Blood 1996 : Like IL-4, IL-13 induces IL-1 receptor antagonist (IL-1Ra) synthesis with no effect on IL-1beta synthesis ... We investigated whether IL-13 induces IL-1Ra synthesis via a pathway similar to IL-4 ... In human peripheral blood mononuclear cells, IL-13 ( 1 to 100 ng/mL alone induced IL-1Ra synthesis in a dose dependent manner ... However, hIL-4.Yl24D inhibited IL-1Ra synthesis induced by either IL-4 or IL-13 ... Accordingly, IL-13 suppressed IL-1beta synthesis but enhanced IL-1Ra synthesis in these cells ... Moreover, IL-13 induced transcriptional activation of the IL-1Ra gene, but reduced IL-1beta gene transcription
Seitz et al., Eur J Immunol 1996 : In resting and cytokine stimulated MNC, IL-13 markedly inhibited IL-1 beta, IL-8 and monocyte chemoattractant protein-1 ( MCP-1 ) release and potently stimulated interleukin-1 receptor antagonist ( IL-1ra ) synthesis
Jovanovic et al., Osteoarthritis Cartilage 1998 (Osteoarthritis) : We examined the effect of IL-13 on the synthesis and expression of interleukin-1 beta (IL-1 beta), tumor necrosis factor-alpha (TNF-alpha), IL-1 receptor antagonist (IL-1Ra) and stromelysin-1 on human OA synovial membrane in ex vivo cultures ... In OA synovial membrane treated with LPS, IL-13 inhibited the synthesis of IL-1 beta, TNF-alpha and stromelysin-1, but increased IL-1Ra production
Gabay et al., Blood 1999 (Liver Neoplasms) : To examine the role of IL-4 and IL-13 in production of IL-1Ra , human primary hepatocytes and HepG2 human hepatoma cells were cultured in the presence of IL-4 or IL-13 in combination with IL-1beta and/or IL-6