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MAP3K1 — MAP3K7
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Hammaker et al., J Immunol 2004
(Arthritis, Rheumatoid...) :
Of interest,
MEKK1 immunoprecipitates from IL-1 stimulated FLS appeared to activate c-Jun through the JNK pathway and
TAK1 activation of c-Jun was
dependent on JNK, ERK, and p38
Wang et al., J Biol Chem 1997
:
However, because the dominant negative mutants of MEKK1 and MLK3 did not inhibit TAK1 induced JNK activity, we conclude that activation of JNK1 by
TAK1 is
independent of
MEKK1 and MLK3