Hagood et al., Am J Pathol 2005
(Pulmonary Fibrosis) :
The fibrogenic cytokines interleukin-1 and tumor necrosis factor-alpha induced loss of fibroblast Thy-1 surface expression in vitro, which was associated with Thy-1 shedding, Smad phosphorylation, and myofibroblast differentiation
Cambos et al., Int J Parasitol 2008
(Anemia...) :
Interestingly, a potent induction of TNF-alpha and IFN-gamma production by CD4+ and CD90 ( - ) lymphocytes was measured in DS-infected mice, which also suffered severe anaemia earlier than non depleted infected controls
Mason et al., J Immunol 1996
:
Inhibition studies showed that the induction of Thy-1 by PBu and TNF was protein synthesis dependent