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CHRFAM7A — IL2

Text-mined interactions from Literome

Levin et al., Lymphokine Res 1989 : Antigen processing and presentation, induction of D10 IL-4 production and proliferation, and IL-2 production demonstrate two different age related patterns of UV-irradiation induced damage : a dose dependent inhibition when adult cells are irradiated and an inverse effect in which low doses of irradiation were more inhibitory than higher doses when neonatal cells are irradiated
Chen et al., J Immunol 1994 : Importantly, in an Ag presentation assay using activated 5C2 cells as APC, the secretion of IL-2 by C8A3 T hybrids was partially inhibited by mAb 2D10 alone and completely blocked by combination use of mAbs 2D10 and 1G10 in a dose dependent and synergistic fashion
Nelson et al., Mol Cell Biol 1996 : To identify the residues of gamma c critical to this process, mutations were introduced into the cytoplasmic domain, and the effects on signalling were analyzed in the IL-2 dependent T-cell line CTLL2 and T-helper clone D10 , using chimeric IL-2R chains that bind and are activated by granulocyte-macrophage colony stimulating factor