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IL12A — RABEPK

Text-mined interactions from Literome

Nagayama et al., J Immunol 2000 : Furthermore, stimulation of DCs with IL-12 induced IL-12p40 transcript, but not IL-12p35 transcript, whereas this stimulation caused the expressions of both transcripts in Con A blasts
Taoufik et al., Eur J Immunol 2001 : IL-12p70 and, more effectively, the combination of IL-12p70 and IFN-gamma, induced IL-12p40 mRNA expression and bioactive IL-12p70 production
Yang et al., Neuroendocrinology 2002 : Both IL-12 p40 gene induction and IL-12 production were also observed when freshly isolated pituitary glands from non treated SD rats were incubated with LPS in vitro
Masumi et al., FEBS Lett 2002 : We have previously shown that IL-12p40 expression is impaired in ICSBP-deficient mice and that transfection of ICSBP together with IRF-1 can activate IL-12p40 expression in mouse macrophage cells
Hensler et al., J Gen Virol 2009 : We detected expression of interleukin (IL)-6, tumour necrosis factor (TNF)-alpha, macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, RANTES and IL-12p40 from 2 to 6 h post-infection, and these peaked by 15-24 h. Expression of these factors decreased 24-48 h post-infection, with the exception of TNF-alpha which remained high throughout the entire 72 h. Interestingly, while IL-12p40 expression increased post-infection, bioactive IL-12p70 was not detected in the supernatants
Gulliver et al., Am J Respir Cell Mol Biol 2011 (Asthma) : The B(1)R agonist Lda-BK was not chemotactic for hMo-DCs matured using LPS, TNF-a + IL-1ß, or CD40 ligand, but Lda-BK enhanced the secretion of IL-12p70 and inhibited the secretion of IL-12p40 by mature hMo-DCs
Kricek et al., Eur J Immunol 1995 : After GAMD injection, two groups of induction profiles were observed in spleen, mesenteric lymph nodes and Peyer 's patches : while IL-4 and IL-12p35 gene transcription was strongly enhanced, IFN-gamma, IL-12p40 and IL-13 mRNA were only moderately induced
Hayes et al., Blood 1995 : These results indicated that both p40 and p35 are LPS-inducible in monocytes following IFN-gamma pretreatment, and that the regulated expression of p35 controls the level of active IL-12 protein in purified human monocytes
Mattner et al., Eur J Immunol 1993 : Only IL-2 + IL-12 but not IL-2 + tumor necrosis factor induced aggregation was inhibited in a dose dependent manner by IL-12p40
Chong et al., Infect Immun 1996 : By 4 h postexposure, viable organisms had induced a 27-fold increase in IL-12 p40 mRNA levels while killed organisms had induced a 9-fold increase in IL-12 p40 mRNA levels
von Stebut et al., J Exp Med 1998 (Leishmaniasis, Cutaneous) : Parasite internalization was associated with activation manifested by upregulation of major histocompatibility complex ( MHC ) class I and II surface antigens, increased expression of costimulatory molecules ( CD40, CD54, CD80, and CD86 ), and interleukin (IL)-12 p40 release within 18 h. L. major induced IL-12 p70 release by DC required interferon gamma and prolonged ( 72 h ) incubation