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CRKL — EPX
Text-mined interactions from Literome
Arai et al., J Biol Chem 2001
:
Overexpression of Lyn induced constitutive phosphorylation of CrkL and activation of Erk, whereas that of a Lyn mutant lacking the tyrosine kinase domain attenuated the
Epo induced phosphorylation of
CrkL and activation of Erk
Chin et al., Biochem Biophys Res Commun 1997
:
Studies using cells expressing mutant EpoRs showed that the
Epo induced tyrosine phosphorylation of
CrkL is dependent on the membrane-proximal EpoR cytoplasmic region involved in the activation of Jak2 as well as the C-terminal 145 amino acid region which is required for tyrosine phosphorylation of SHP-2 and Shc