◀ Back to IFNG

A2M — IFNG

Text-mined interactions from Literome

Magielska-Zero et al., Biochem Int 1988 (Carcinoma, Hepatocellular...) : In distinction, recombinant human interferon-gamma profoundly inhibits synthesis of alpha 1-antichymotrypsin, and especially of haptoglobin, but stimulates production of alpha 2-macroglobulin thus modulating the acute phase response of these cells
Yuan et al., Mol Cell Biol 1994 : We report here that the rat alpha 2-macroglobulin promoter is activated by IFN-gamma in human hepatoma ( HepG2 ) cells and that the IFN-gamma response element maps to the same site previously defined as the acute-phase response element ( APRE ), which binds the IL-6 activated transcription factor APRF ( acute-phase response factor )
Fabrizi et al., J Neuroimmunol 1994 (Astrocytoma) : Interferon gamma (IFN gamma) , a potent immunoregulatory lymphokine, was able to increase the synthesis of alpha 2M by these cells, as measured by ELISA on cell supernatants