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Text-mined interactions from Literome

Rao et al., J Biol Chem 1999 : To understand the role of redox-sensitive mechanisms in vascular smooth muscle cell ( VSMC ) growth, we have studied the effect of N-acetylcysteine (NAC) , a thiol antioxidant, and diphenyleneiodonium ( DPI ), a potent NADH/NADPH oxidase inhibitor, on serum-, platelet derived growth factor BB-, and thrombin induced ERK2, JNK1, and p38 mitogen activated protein ( MAP ) kinase activation ; c-Fos, c-Jun, and JunB expression ; and DNA synthesis
Kyaw et al., Hypertens Res 2001 (MAP Kinase Signaling System) : In contrast, p38 MAPK activation was inhibited by DPI and ascorbic acid concentration-dependently, but by NAC only at high concentration
Wang et al., Free Radic Biol Med 2003 : The phosphorylation of p38 MAPK by V2O5 was inhibited by NAC and catalase, yet the EGF receptor inhibitor AG1478 had no effect on V2O5 induced p38 MAPK activation
Shastry et al., Kidney Int 2007 : In addition, Hcy induced apoptosis as determined by TUNEL and ssDNA assay was abrogated by Nac , Cat, and SB203580 ( p38-MAPK inhibitor )
Luo et al., Nephrol Dial Transplant 2008 (Acute Kidney Injury...) : NAC blocked oxidative stress, p38 MAPK activation, caspase-3 cleavage, tissue apoptosis, renal dysfunction and morphological damage induced by CDDP
Huang et al., J Pharmacol Sci 2008 (Carcinoma, Hepatocellular...) : Moreover, the ROS activated the p38 kinase, which in turn promoted the activation of p53, as verified by evidence showing that the ROS scavenger N-acetyl-cysteine (NAC) not only blocked the phosphorylation of p38 but also partially inhibited the activation of p53, and the p38 inhibitor SB203580 reduced the activation of p53 as well
Iftakhar-E-Khuda et al., Clin Exp Immunol 2009 (Niemann-Pick Diseases) : U18666A led to the phosphorylation of p38 mitogen activated protein kinase 24 and 48 h after the stimulation and the p38 activation was inhibited in presence of cholesterol-free medium or NAC
Franchi et al., J Invertebr Pathol 2013 (MAP Kinase Signaling System) : We studied in vitro zymosan phagocytosis in the presence of manumycin A, which inhibit the activation of Ras, PD98059, SP600125 and SB202190, inhibitors of Erk, JNK and p38 , respectively, parthenolide, N-acetyl-l-cysteine (NAC) and pyrrolidine dithiocarbamate ( PDTC ), inhibiting NF-kB activation