Gene interactions and pathways from curated databases and text-mining

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IL15 — STAT6

Text-mined interactions from Literome

Masuda et al., J Biol Chem 2000 : Interleukin-15 induces rapid tyrosine phosphorylation of STAT6 and the expression of interleukin-4 in mouse mast cells
Masuda et al., J Biol Chem 2001 : We recently reported that IL-15 induces STAT6 activation and IL-4 production in a mouse mast cell line ( MC/9 ) and bone marrow derived mast cells ... In an electrophoretic mobility shift assay, IL-15 induced STAT6 binding to the STAT recognition site in the bcl-x ( L ) gene promoter
Hale et al., PloS one 2009 (Disease Progression...) : We report that robust changes in cytokine signal transduction occur during the progression of SLE in multiple immune cell subtypes including increased T cell responsiveness to IL-10 and ablation of Stat1 responses to IFNalpha, IFNgamma, IL-6, and IL-21, Stat3 responses to IL-6, Stat5 responses to IL-15 , and Stat6 responses to IL-4