da Costa et al., Curr Alzheimer Res 2005
(Alzheimer Disease) :
The aim of this review is to focus on the mechanisms by which presenilin 2 affects the programmed cell death with special emphasis on the role of the proteolytically derived presenilin fragments generated by both presenilinase- and caspases
Janicki et al., J Cell Biol 1997
(Alzheimer Disease) :
Although HeLa cells are strongly predisposed to continued mitosis, expression of PS-2 induced programmed cell death ( apoptosis )