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CDH1 — GSK3B
Text-mined interactions from Literome
Imanishi et al., Cancer Res 2007
(Breast Neoplasms...) :
Using a xenograft model, we show that overexpression of Ang2 in poorly metastatic MCF-7 breast cancer cells suppresses expression of
E-cadherin and
induces Snail expression and phosphorylation of Akt and
glycogen synthase kinase-3beta ( GSK-3beta ) promoting metastasis to the lymph nodes and lung
Farina et al., PloS one 2009
(Breast Neoplasms...) :
Here we show that cell density and
GSK-3beta regulate
cadherin-11 levels in cancer cells ... Our data show that
GSK3beta regulates
cadherin-11 expression in two ways : first a beta-catenin independent regulation of cadherin-11 steady state mRNA levels, and second a beta-catenin dependent effect on cadherin-11 3'UTR stability and protein translation