Gene interactions and pathways from curated databases and text-mining

◀ Back to CDH1

CDH1 — GSK3B

Text-mined interactions from Literome

Imanishi et al., Cancer Res 2007 (Breast Neoplasms...) : Using a xenograft model, we show that overexpression of Ang2 in poorly metastatic MCF-7 breast cancer cells suppresses expression of E-cadherin and induces Snail expression and phosphorylation of Akt and glycogen synthase kinase-3beta ( GSK-3beta ) promoting metastasis to the lymph nodes and lung
Farina et al., PloS one 2009 (Breast Neoplasms...) : Here we show that cell density and GSK-3beta regulate cadherin-11 levels in cancer cells ... Our data show that GSK3beta regulates cadherin-11 expression in two ways : first a beta-catenin independent regulation of cadherin-11 steady state mRNA levels, and second a beta-catenin dependent effect on cadherin-11 3'UTR stability and protein translation