Bower et al., Cell cycle (Georgetown, Tex.) 2010
:
Western immunoblot analysis demonstrated that treatment with ICRF-193 induced ATM autophosphorylation and ATM dependent phosphorylation of Ser15-p53 and Thr68 in Chk2, but no appreciable phosphorylation of Ser139-H2AX or Ser345-Chk1
Gao et al., J Virol 2010
(Coxsackievirus Infections) :
We further demonstrated that REG? mediated p53 proteolysis contributes, as least in part, to the proviral function of REG?
Li et al., Proc Natl Acad Sci U S A 2013
(Aging, Premature) :
Our recent studies suggest a role for the proteasome activator REG ( 11S regulatory particles, 28-kDa proteasome activator ) ? in the regulation of tumor protein 53 (p53)