Fujisawa et al., J Asthma 2002
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Theophylline inhibited IL-5 induced release of EDN in a concentration dependent manner
Ohshima et al., Int Arch Allergy Immunol 2002
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LTE ( 4 ) also induced significant eosinophil migration at 10 ( -6 ) M. LTD ( 4 ) enhanced EDN release induced by IL-5 via CysLT ( 1 )
Matsuwaki et al., Pharmacology 2005
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We investigated the effect of a PPARgamma agonist on human eosinophil functions such as IL-5 induced CD69 surface expression and EDN release ... IL-5 induced eosinophil CD69 surface expression and EDN release were significantly inhibited by the synthetic PPARgamma agonist troglitazone, and these effects were reversed by a PPARgamma antagonist
Ito et al., Int Arch Allergy Immunol 2008
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Treatment with HGF suppressed interleukin-5 induced upregulation of CD69 expression, ROS production and EDN release from human eosinophils