Gene interactions and pathways from curated databases and text-mining

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IL6 — MBP

Text-mined interactions from Literome

Haggiag et al., J Neurosci Res 2001 : IL6RIL6 induces Po and MBP in CH cells and their cocultures with neurons
Miller et al., Int J Dev Neurosci 2010 (Prenatal Exposure Delayed Effects) : Instead, IL-6 may contribute to increased MBP levels in males, whereas in females estromimetic and thyromimetic PCB metabolites may affect white matter development
Selmaj et al., Clin Exp Immunol 1988 (Multiple Sclerosis) : Multiple sclerosis : effect of myelin basic protein on interleukin 1, interleukin 2 production and interleukin 2 receptor expression in vitro
Arai et al., Q J Med 1993 (Acute-Phase Reaction...) : MBP mRNA expression in HuH-7 cells was increased by interleukin-6 (IL-6) , dexamethasone and heat shock, decreased by interleukin 1 (IL-1), and unaffected by interferon gamma (IFN gamma), tumour necrosis factor alpha (TNF alpha) and transforming growth factor beta ( TGF beta )
Rochester et al., J Immunol 1996 : To test the hypothesis that eosinophil major basic protein (MBP) is an important regulator of fibroblast effector function, we characterized the effects of MBP on human lung fibroblast production of the IL-6-type cytokines, IL-6 , IL-11, and leukemia inhibitory factor ... These studies demonstrate that MBP interacts in a synergistic fashion with rIL-1-alpha or TGF-beta(1) to further augment fibroblast IL-6-type cytokine production