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IFNG — PTPRC
Text-mined interactions from Literome
Blank et al., J Immunol 2001
:
Costimulation with OKT-3 and IL-2 optimally
induced secretion of
IFN-gamma , TNF-alpha, and IL-5, which was not decreased by
CD45 signals
MacKenzie et al., Transplant Proc 2003
:
Depletion of
CD45 ( + ) cells
resulted in the low levels of
IFNgamma production at early time points ( day 4 ), which increased to near normal levels by day 7
Huang et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2004
(Myelodysplastic Syndromes) :
The results showed that TNF-alpha,
IFN-gamma levels in BM of MDS both
increased , the former produced by cells
CD4+CD45RO+ , CD8+CD45RO+, the latter by cells CD4+CD45RO+, CD8+CD45RO+, CD8+CD45RA+, in which the cells CD8+CD45RO+ were dominant
Komai-Koma et al., Eur J Immunol 2009
:
Moreover, CD8 ( + )
CD45RO ( + ) memory T cells constitutively expressed TLR4 and markedly
enhanced IFN-gamma production when stimulated with LPS
Jang et al., J Leukoc Biol 2009
:
Furthermore, production of IL-23 in CBDC costimulated with LPS and IL-12 caused CD4 ( + )
CD45RO ( + ) memory cells to
increase IFN-gamma production
Brod et al., J Exp Med 1989
:
CD45RA expression could be further
regulated by ionomycin or the cytokines IL-1 and IL-6, but not IL-2, IL-4, or
IFN-gamma
Xu et al., J Immunol 1995
:
Cross linking of
CD45 on NK cells
stimulates p56lck mediated tyrosine phosphorylation and
IFN-gamma production
Shen et al., J Immunol 1995
:
We report here that cross linking of
CD45 specifically
stimulates IFN-gamma production in human NK cells