Gaubin et al., J Immunol 1999
(Breast Neoplasms) :
We show here that gp17/GCDFP-15 is in fact a strong and specific inhibitor of the T lymphocyte programmed cell death induced by CD4 cross linking and subsequent TCR activation
Winkler et al., J Virol 1999
(Acute Disease...) :
Bovine herpesvirus 1 can infect CD4 ( + ) T lymphocytes and induce programmed cell death during acute infection of cattle
Vasquez et al., Immunity 1994
:
Antigenic stimulation of CD4/CD8 double positive ( DP ) thymocytes results in programmed cell death , while the identical stimulation of mature T cells results in proliferation and lymphokine secretion
Siliciano et al., Curr Top Microbiol Immunol 1996
:
In addition, shed gp120 can bind to CD4 on noninfected cells and interfere with the function of these cells while at the same time rendering the cells susceptible to destruction by ADCC, by CD4+ CTLs or by programmed cell death induced by cross linking of CD4 with gp120 and anti-gp120 followed by cellular activation