◀ Back to HDAC1

CD40LG — HDAC1

Text-mined interactions from Literome

Mishra et al., Proc Natl Acad Sci U S A 2001 (Lupus Erythematosus, Systemic) : Here, we demonstrate that the histone deacetylase inhibitor, trichostatin A, significantly down-regulated CD154 and IL-10 and up-regulated IFN-gamma gene expression in SLE T cells
Skov et al., Blood 2003 (Autoimmune Diseases...) : HDAC-i furthermore inhibited activation induced CD25 and CD154 expression on CD4 cells, without affecting induction of CD69 ... HDAC-i inhibited CD154 expression by a mechanism distinctly different from cyclosporine mediated inhibition ... HDAC-i thus inhibited interleukin 2 (IL-2) induced CD154 expression on effector T cells and constitutively expressed CD154 on various tumor cells, events that were not affected by cyclosporine