Gene interactions and pathways from curated databases and text-mining

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ARG1 — NOX1

Text-mined interactions from Literome

Morris et al., Br J Haematol 2000 (Acute Disease...) : L-Arg ( 0.1 g/kg ) increased NOx formation by 18.8 +/- 68 % in normal controls, whereas steady-state SCD patients demonstrated a paradoxical decrease in NOx of -16.7 +/- 4 % ( P = 0.004 )
Zhan et al., J Histochem Cytochem 2003 : L-Arg ( 100 microM ) increased NOx levels significantly ( p < 0.05 ) ... In explants exposed to inhibitors of NOS, the effect of l-Arg on the production of NOx was blocked
Zhang et al., Am J Pathol 2009 (Disease Models, Animal...) : In conclusion, these studies suggest that LPS induced retinal inflammation in endotoxin induced uveitis is mediated by NADPH oxidase dependent increases in arginase activity
Caldwell et al., Brain Res Bull 2010 (Retinal Neovascularization) : Furthermore, the induction of arginase during retinopathy is blocked by knocking out NOX2 or inhibiting NADPH oxidase activity
Shin et al., The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2011 : In HUVECs, inhibition of arginase activity by CLE reciprocally increased NOx production through enhancement of eNOS dimer stability without any significant changes in the protein levels of eNOS and arginase II expression
Yabuki et al., Brain Res 2013 (Disease Models, Animal...) : In addition, we devised a novel protocol to analyze NOx ( - ) ( NO ( 2- ) and NO ( 3- ) ) productions following L-Arg infusion using in vivo microdialysis and revealed that decreased L-Arg induced NOx ( - ) levels were improved in the hippocampus of BCCAO mice following repeated L-Cit administration
Verhoeven et al., J Biol Chem 1993 : In electropermeabilized neutrophils, the myristoylated pseudosubstrate Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln ( myr-psi PKC ) inhibited PMA induced protein phosphorylations and activation of the NADPH oxidase , induced either by PMA or by the receptor agonist formyl-methionyl-leucyl-phenylalanine