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CREB1 — HGF

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: CREB1 → HGF (increases) Ma et al., Br J Cancer 2007*
  Evidence: In c-MET-overexpressing SCLC cell line NCI-H69, hepatocyte growth factor (HGF) dramatically induced c-MET phosphorylation at phosphoepitopes pY1230/1234/1235 (catalytic tyrosine kinase), pY1003 (juxtamembrane), and also of paxillin at pY31 (CRKL-binding site). We utilised a global proteomics phosphoantibody array approach to identify further c-MET/HGF signal transduction intermediates in SCLC. Strong HGF induction of specific phosphorylation sites in phosphoproteins involved in c-MET/HGF signal ...

Text-mined interactions from Literome

Hossain et al., J Neurochem 2002 : Neither SF/HGF nor FGF-1 activated cyclic AMP-response element binding protein ( CREB ), a downstream target of MAP-kinase, whereas brain derived neurotrophic factor (BDNF) activated both MAP-kinase and CREB in granule neurons
Tan et al., J Am Soc Nephrol 2007 (MAP Kinase Signaling System) : Chromatin immunoprecipitation assay revealed that activated CREB and Sp1 bound to their cognate cis acting elements in SnoN promoter in response to HGF stimulation ... Furthermore, HGF selectively induced CREB phosphorylation in HKC-8 cells but not in mesangial cells and fibroblasts