◀ Back to ANGPT2

ANGPT2 — SMAD1

Text-mined interactions from Literome

Mima et al., Lab Invest 2006 (Diabetes Mellitus, Experimental...) : Here we examined the effect of Ang II on the expression of Smad1 and mesangial matrix expansion in streptozotocin (STZ) induced diabetic rats in vivo, using Ang II type 1 receptor blocker, olmesartan ... Ang II induced Col4 synthesis and increased expression of phospho-Src and phospho-Smad1 in cultured mesangial cells, which was blocked by olmesartan
Zhang et al., Hypertension 2010 (Fibrosis...) : Enhanced upregulation of the Ang II type I receptor and activation of the transforming growth factor-beta/Smad and nuclear factor-kappaB signaling pathways may be the mechanisms by which CRP promotes cardiac fibrosis and inflammation under high Ang II conditions