Rocic et al., Am J Physiol Cell Physiol 2001
(Hypertrophy) :
ANG II caused a rapid and Ca ( 2+ ) -dependent tyrosine phosphorylation of the adapter molecule p130Cas , which coimmunoprecipitated both PYK2 and PI 3-kinase in ANG II-treated VSMC
Takahashi et al., Am J Physiol 1998
:
These results indicate that ANG II induces tyrosine phosphorylation of p130Cas and c-Crk II and their specific association, suggesting a potential role of the p130Cas-c-Crk II complex in ANG II signal transduction in VSMC