Yu et al., FASEB J 2010
:
Furthermore, down-regulation of miR-205 resulted in an increase in Rho-ROCKI activity, phosphorylation of the actin severing protein cofilin , and a corresponding diminution of filamentous actin
Luo et al., Journal of translational medicine 2013
(Breast Neoplasms...) :
We characterized one of the target genes of miR-200c, CFL2, and demonstrated that CFL2 is overexpressed in aggressive breast cancer cell lines and can be significantly down-regulated by exogenous miR-200c