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ADCYAP1 — PENK

Text-mined interactions from Literome

Just et al., Glia 2000 : In the neocortical part of the slice cultures, the effect of PACAP38 on PEnk gene expression was inhibited only by H89 and PD98059 ... It is concluded that PACAP38 induced the PEnk gene expression in both culture systems in a cell-type specific manner
Monnier et al., DNA Cell Biol 1998 : Both ligands stimulated PENK gene transcription in a dose dependent manner, with an apparent ED50 close to 5 x 10 ( -11 ) M. Inactivation of cAMP dependent-protein kinase (PKA) with a dominant inhibitory mutant strongly reduced PACAP stimulated PENK transcription ... Taken together, these results indicate that PACAP stimulates PENK transcription by members of both the AP1 and the CREB families