Gene interactions and pathways from curated databases and text-mining

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EPHB2 — OCLN

Text-mined interactions from Literome

Campbell et al., Curr Eye Res 2006 : Inhibition of p38 MAPK and ERK1/ERK2 prevented endostatin 's ability to upregulate levels of occludin expression
Reijerkerk et al., J Immunol 2008 (Encephalomyelitis, Autoimmune, Experimental) : Importantly, live imaging and immunoblot analyses of rat brain endothelial cells revealed that tPA and ERK1/2 control the breakdown of the tight junction protein occludin
Cohen et al., PloS one 2010 (MAP Kinase Signaling System...) : Expression of claudin 4, claudin 18, and occludin was significantly lower, and activation of JNK and ERK signaling pathways was significantly increased in 2CLP monolayers, relative to sham monolayers
Mohammad et al., Exp Eye Res 2013 (Diabetes Mellitus, Experimental...) : Diabetes induced significant upregulation of the expression of HMGB-1, receptor for advanced glycation end products ( RAGE ), ERK ( 1/2 ) and nuclear transcription factor Kappa B ( NF-?B ), whereas the expression of toll-like receptor 2 (TLR2) and occludin was significantly downregulated