Gene interactions and pathways from curated databases and text-mining

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FGF2 — IL11

Text-mined interactions from Literome

Bodo et al., Eur J Cell Biol 1999 (Craniofacial Dysostosis) : ELISA showed that bFGF induced interleukin secretion differed in normal and Crouzon osteoblasts
Im et al., J Biol Chem 2007 : bFGF stimulation of MMP-13 was mediated at the transcriptional level and, at least in part, by stimulation of interleukin-1 production
Nakayama et al., J Oral Sci 2012 : In human osteoblast-like Saos2 cells, FGF2 increased the expression of the osteopontin ( SPP1, 16.7-fold ), interleukin-8 ( IL8, 6.4-fold ) and IL11 ( 4.8-fold ) genes
Chandrasekhar et al., J Cell Physiol 1989 : Induction of interleukin-1 receptors on chondrocytes by fibroblast growth factor : a possible mechanism for modulation of interleukin-1 activity
Iwamoto et al., Immunol Lett 1989 : Furthermore, interleukin 1 (IL-1) suppressed by 50-60 % the incorporation of [ 3H ] thymidine into DNA in high density chondrocyte cultures on plastic dishes in the presence of 10 % serum or fibroblast growth factor , although it increased twofold this incorporation in 0.3 % serum alone
Norioka et al., Jpn J Cancer Res 1994 (Neovascularization, Pathologic) : Interaction of interleukin-1 and interferon-gamma on fibroblast growth factor induced angiogenesis
Tamura et al., Endocrinology 1996 (Arthritis...) : Nitric oxide mediates interleukin-1 induced matrix degradation and basic fibroblast growth factor release in cultured rabbit articular chondrocytes : a possible mechanism of pathological neovascularization in arthritis
Nakamura et al., J Hypertens 1996 : bFGF , TGF-beta, interleukin-1 alpha, -1 beta and -6 stimulated DNA synthesis in VSMC significantly, whereas HGF did not
Sasaki et al., J Biochem 1998 : Nitric oxide mediates interleukin-1 induced gene expression of matrix metalloproteinases and basic fibroblast growth factor in cultured rabbit articular chondrocytes
Lacroix et al., Cancer Lett 1998 (Breast Neoplasms) : The production of Il-11 was increased by transforming growth factor-beta1 in a dose dependent manner with a rapid ( 2 h ) and transient ( 24 h ) mRNA induction, but not by epidermal growth factor, insulin-like growth factor-I and -II, basic fibroblast growth factor , platelet derived growth factor or parathyroid hormone