Gene interactions and pathways from curated databases and text-mining

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RAC1 — SERPINF1

Text-mined interactions from Literome

Yoshida et al., FEBS Lett 2006 (Carcinoma, Hepatocellular) : We found here that AGEs upregulated CRP mRNA levels in cultured Hep3B cells via Rac-1 activation, which was blocked by pigment epithelium derived factor (PEDF)
Yoshida et al., Life Sci 2006 : PEDF was also found to inhibit the IL-6 elicited Rac-1 activation, whereas dominant negative Rac-1 dose-dependently decreased the CRP mRNA levels