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GDI2 — RAC1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: Complex of 400 proteins (association, cross-linking study) Humphries et al., Science signaling 2009

Text-mined interactions from Literome

Gorzalczany et al., J Biol Chem 2000 : Amphiphile and p47(phox) independent NADPH oxidase activation by prenylated Rac1 is inhibited by Rho GDP dissociation inhibitor and by phosphatidylcholine vesicles, both competing with membrane for prenylated Rac1
Di-Poï et al., Biochemistry 2001 : These data suggest that Rho-GDI stabilizes Rac in an active conformation, even in the GDP bound state, and presents it to its effector, the p67phox component of the NADPH oxidase
Groysman et al., J Biol Chem 2002 : Surprisingly, Vav1 associates with Ly-GDI , a hematopoietic cell-specific guanine nucleotide dissociation inhibitor of Rac