Gene interactions and pathways from curated databases and text-mining

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MDM2 — RPS6KB1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Fang et al., J Cell Physiol 2006 : Overexpression of p70S6K1 enhanced HDM2 phosphorylation and led to an increase in HDM2 protein turnover
Jia et al., Cell Death Differ 2013 : IKK-ß and p85 S6K1 contributed to H ( 2 ) O ( 2 ) -induced phosphorylation of Mdm2 ( S166 ) and p53 accumulation