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MC3R — MSH2
Text-mined interactions from Literome
Getting et al., FASEB J 2006
(Arthritis, Experimental...) :
In wild-type ( WT ) macrophages, [ D-Trp8 ]
-gamma-MSH activated
MC3-R ( as tested by accumulation of cyclic AMP ) and inhibited ( approximately 50 % ) the release of interleukin (IL)-1 and the chemokine KC ( CXCL1 ), but was ineffective in cells taken from MC3-R null mice
Lee et al., Peptides 2008
:
We now demonstrate that central
activation of
MC3-R with ICV infusion of the specific MC3-R agonist, [ D-Trp ( 8 ) ]
-gamma-MSH , transiently suppresses hypothalamic Pomc expression and stimulates food intake in rats