Gene interactions and pathways from curated databases and text-mining

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HCL2 — TNF

Text-mined interactions from Literome

Kamata et al., FEBS Lett 2001 : Luciferase gene reporter assays revealed that cPrG.HCl potently suppressed the TNFalpha- and the phorbol myristate acetate induced activation of NF-kappaB
Foa et al., J Clin Oncol 1992 (Leukemia, Hairy Cell) : In view of the pleomorphic role cytokines play in human lymphoproliferative disorders, we investigated the possible involvement of tumor necrosis factor-alpha (TNF) in hairy cell leukemia ( HCL )
Sakai et al., Life Sci 2010 (Edema) : GlcN-HCl and GlcNAc significantly suppressed the antigen induced up-regulation of TNF-alpha and IL-6 mRNA
Barut et al., Blood 1990 (Leukemia, Hairy Cell) : DNA synthesis induced by TPA/Ca2+ was blocked specifically by anti-IL-6 Ab ; in contrast, the HCL proliferative response to SAC, TNF , or IL-4 and IL-5 was not inhibited by anti-IL-6 Ab. alpha-Interferon inhibited the response to TPA/Ca2+, TNF, or IL-4 and IL-5 without any effect on response to SAC
Sudo et al., Nihon Ronen Igakkai Zasshi 1993 (Acute Disease...) : These findings suggest that TNF alpha and elastase play a significant role in HCl and LPS induced acute lung injury
Demeter et al., Br J Haematol 1997 (Leukemia, Hairy Cell) : The pathogenetic role of tumour necrosis factor (TNF)-alpha in HCL prompted us to study the potential contribution of functionally important genetic polymorphisms of the TNF gene cluster in a large group of patients with HCL