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HCL2 — TNF
Text-mined interactions from Literome
Kamata et al., FEBS Lett 2001
:
Luciferase gene reporter assays revealed that
cPrG.HCl potently
suppressed the
TNFalpha- and the phorbol myristate acetate induced activation of NF-kappaB
Foa et al., J Clin Oncol 1992
(Leukemia, Hairy Cell) :
In view of the pleomorphic role cytokines play in human lymphoproliferative disorders, we investigated the possible
involvement of
tumor necrosis factor-alpha (TNF) in
hairy cell leukemia ( HCL )
Sakai et al., Life Sci 2010
(Edema) :
GlcN-HCl and GlcNAc significantly
suppressed the antigen induced up-regulation of
TNF-alpha and IL-6 mRNA
Barut et al., Blood 1990
(Leukemia, Hairy Cell) :
DNA synthesis induced by TPA/Ca2+ was blocked specifically by anti-IL-6 Ab ; in contrast, the
HCL proliferative
response to SAC,
TNF , or IL-4 and IL-5 was not inhibited by anti-IL-6 Ab. alpha-Interferon inhibited the response to TPA/Ca2+, TNF, or IL-4 and IL-5 without any effect on response to SAC
Sudo et al., Nihon Ronen Igakkai Zasshi 1993
(Acute Disease...) :
These findings suggest that
TNF alpha and elastase
play a significant role in
HCl and LPS induced acute lung injury
Demeter et al., Br J Haematol 1997
(Leukemia, Hairy Cell) :
The pathogenetic
role of
tumour necrosis factor (TNF)-alpha in
HCL prompted us to study the potential contribution of functionally important genetic polymorphisms of the TNF gene cluster in a large group of patients with HCL