Gene interactions and pathways from curated databases and text-mining

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CD36 — FOS

Text-mined interactions from Literome

Lee et al., Life Sci 2009 : Up-regulation of SR-A and CD36 by resistin resulted from activation of AP-1 and PPARgamma, respectively, and this was confirmed by the lack of activation of either after AP-1 inhibition using curcumin or SP600125, or PPARgamma inhibition using GW9662, respectively
Li et al., Int J Mol Med 2013 : The reduced CD36 expression following kaempferol treatment involved the inhibition of c-Jun-activator protein-1 (AP-1) nuclear translocation ... The inhibition of AP-1 using the inhibitor, SP600125, confirmed this involvement, as the AP-1 inhibition significantly augmented the kaempferol induced reduction in CD36 expression ... In conclusion, the c-Jun-AP-1 dependent downregulation of CD36 and the HO-1 dependent upregulation of ABCG1, SR-BI and ABCA1 may mediate the beneficial effects of kaempferol on foam cell formation