Gene interactions and pathways from curated databases and text-mining

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CRK — PDCD11

Text-mined interactions from Literome

El-Bikai et al., Arthritis Res Ther 2010 (Osteoarthritis) : It inhibited a1ß1 integrin and Col II expression as well as ERK1/2 and NF-?B-p65 phosphorylation, but, in contrast, markedly elicited PGE2 release, COX-2 expression and p38 MAPK phosphorylation
Kim et al., J Med Food 2011 : PCP increased the degradation of inhibitor of nuclear factor-?B ( NF-?B ) a/ß, which enhanced the nuclear translocation of NF-?B p50/p65 and induced the phosphorylation of extracellular signal regulated kinase, c-Jun N-terminal kinase, and p38 mitogen activated protein kinases, which are signaling molecules downstream of TLR4
Song et al., Fitoterapia 2013 (Inflammation) : HSYA treatment also decreased NF-?B p65 nuclear translocation and inhibited the phosphorylation of p38 mitogen activated protein kinase ( p38 MAPK )