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CD8A — IL23A

Text-mined interactions from Literome

Belladonna et al., J Immunol 2002 : While both proteins induce IL-12 production from DC, only IL-23-Ig can act directly on CD8alpha ( + ) DC to promote immunogenic presentation of an otherwise tolerogenic tumor peptide
Overwijk et al., J Immunol 2006 (Weight Loss) : Upon specific vaccination, however, systemic IL-23 greatly increased the relative and absolute numbers of vaccine induced CD8 ( + ) T cells and enhanced their effector function at the tumor site
Jin et al., Cancer Gene Ther 2008 (Neoplasms) : Interestingly, whereas IL-23 still induced tumor-specific CD8 ( + ) T-cell responses, it could not activate natural killer ( NK ) cells in vitro and in vivo
Henry et al., J Immunol 2008 : Therefore, we sought to determine the individual roles of IL-12 and IL-23 in naive CD8 ( + ) T cell activation by addressing their ability to influence IFN-gamma production and cellular interaction dynamics during priming by Listeria monocytogenes infected dendritic cells ( DC )
Reay et al., Cancer Gene Ther 2009 (Fibrosarcoma) : In addition, we have shown that the antitumor activity of IL-23 is independent of IL-17, perforin and Fas ligand, but dependent on interferon-gamma, CD4 ( + ) and CD8 ( + ) T cells