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BAX — HSPD1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Arya et al., J Biosci 2007
:
Cytosolic
Hsp60 prevents translocation of the pro-apoptotic protein
Bax into mitochondria and thus promotes cell survival but it also promotes maturation of procaspase-3,essential for caspase mediated cell death
Wang et al., Bone 2011
(Osteoporosis) :
HSP60 gene transfer activated ERK and Akt and
reduced Bax and cytochrome c release, as well as caspase-3 cleavage, which attenuated the inhibitory effects of glucocorticoid treatment on osteoblast survival