Gene interactions and pathways from curated databases and text-mining

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NANOG — PIK3R1

Text-mined interactions from Literome

Nur-E-Kamal et al., Stem Cells 2006 : Inhibitors of PI3K reduced the expression level of Nanog in mESCs cultured on 3D nanofibrillar surfaces
Storm et al., J Biol Chem 2007 : Furthermore, GSK-3 mutants mimicked the effects of PI3K or GSK-3 inhibition on Nanog expression
Kim et al., Arch Pharm Res 2010 : These data suggest that RA-induced PI3K/Akt activation in the early stage of differentiation is required for Nanog expression, which becomes independent of PI3K/Akt signaling once the differentiation is established