Gene interactions and pathways from curated databases and text-mining

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CDK2 — FOS

Text-mined interactions from Literome

Sunters et al., J Biol Chem 2004 : Ectopic c-Fos resulted in increased expression of cyclins A and E protein levels, and premature activation of cyclin A-, cyclin E-, and cyclin dependent kinase (CDK) 2-associated kinase activities, although cyclin D levels and CDK4 activity were not affected significantly in these cell lines
Jalili et al., J Natl Cancer Inst 2012 (MAP Kinase Signaling System...) : Using a dominant negative approach, in vitro cell proliferation assays, western blots, and flow cytometry showed that MAPK signaling via BRAF ( V600E ) promotes melanoma cell proliferation at G1 through AP-1 mediated negative regulation of the INK4 family member, cyclin dependent kinase inhibitor 2C ( CDKN2C ), and the CIP/KIP family member, cyclin dependent kinase inhibitor 1A ( CDKN1A )