Gene interactions and pathways from curated databases and text-mining

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MMP9 — RUNX2

Text-mined interactions from Literome

Pratap et al., Mol Cell Biol 2005 (Bone Neoplasms...) : The overexpression of Runx2 by adenovirus delivery in nonmetastatic ( MCF-7 ) and metastatic breast ( MDA-MB-231 ) and prostate ( PC3 ) cancer cell lines significantly increases the endogenous levels of MMP9 ... Importantly, we have demonstrated using a cell invasion assay that Runx2 regulated MMP9 levels are functionally related to the invasion properties of cancer cells
Hayami et al., Matrix Biol 2011 : In contrast, MMP-13 overexpression resulted in significant decreases in Runx2 , OP and BSP, and increases in TGF-ß1, MSX2 and OC
Li et al., Invest Ophthalmol Vis Sci 2011 : DEX reduced total A ( 1 ) AR-triggered MMP release, and CCD increased the active form of MMP-2 release