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BDNF — CRH

Text-mined interactions from Literome

Ma et al., Chin J Physiol 1999 : Corticotropin releasing factor enhances brain derived neurotrophic factor gene expression to facilitate memory retention in rats ... In the present study, we investigated the effects of corticotropin releasing factor (CRF) injected into the dentate gyrus ( DG ) of the hippocampus on brain derived neurotrophic factor (BDNF) mRNA expression and studied whether N-methyl-D-aspartate ( NMDA ) receptor mediates the effects of CRF on BDNF mRNA expression in the DG ... MK801, at a dose having no significant effect alone ( 0.08 microg ), significantly antagonized the effect of CRF on BDNF mRNA expression
Bayatti et al., Endocrinology 2005 : Corticotropin releasing hormone mediated induction of intracellular signaling pathways and brain derived neurotrophic factor expression is inhibited by the activation of the endocannabinoid system ... Therefore, we analyzed the effects of CRH and the CB1 agonist WIN-55,212-2 on BDNF expression in primary cerebellar neurons from rats and mice ... Pharmacological analysis demonstrated that the CRHR1 antagonist R121919, the protein kinase A inhibitor H89, and the calcium chelator 1,2-bis ( 2-aminophenoxy ) ethane-N, N,N ', N'-tetraacetic acid acetoxymethyl ester inhibited CRH mediated BDNF expression
Toriya et al., J Neuroendocrinol 2010 (Body Weight) : Intracerebroventricular BDNF up-regulated mRNA expression of corticotrophin releasing hormone (CRH) and urocortin in the PVN
Xiao et al., PloS one 2011 (Genetic Predisposition to Disease...) : Corticotropin releasing hormone (CRH) regulates brain derived neurotrophic factor (BDNF) expression through influencing cAMP and Ca2+ signaling pathways during the course
Jeanneteau et al., Proc Natl Acad Sci U S A 2012 : Significantly, ectopic expression of BDNF in vivo increased CRH , whereas reduced expression of BDNF, or its receptor TrkB, decreased CRH expression and normal HPA functions
Gotoh et al., J Neurochem 2013 (Anorexia...) : These results indicate that CRF and hypothalamic neuronal histamine mediate the suppressive effects of BDNF on feeding behavior and body weight