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NOS1 — PGF
Text-mined interactions from Literome
Boiti et al., J Endocrinol 2000
:
On day-9 CL, PGE-2 was ineffective, but
PGF-2alpha caused a 2.5-fold increase of
NOS activity and a marked decrease in progesterone production
Skarzynski et al., Biol Reprod 2000
:
Although an
NO synthase (NOS) inhibitor ( L-NAME )
reduced TNFalpha stimulated
PGF ( 2alpha ) production, an inhibitor of phosphodiesterase augmented the actions of TNFalpha and S-NAP ( P < 0. 05 )
Zerani et al., J Endocrinol 2005
:
Both leptin and NO donor inhibited PGE2 release, whereas they enhanced PGF2alpha release ;
NOS inhibitor alone or with leptin
increased PGE2 and decreased
PGF2alpha production ; NOS activity was enhanced by leptin, while PGs did not affect this enzyme
Weems et al., Prostaglandins Other Lipid Mediat 2005
:
Two experiments were conducted to determine the
effects of NO donors, endothelin-1 (ET-1), and
NO synthase (NOS) inhibitors on bovine caruncular endometrial secretion of PGE and
PGF2alpha in vitro
Lee et al., J Reprod Dev 2009
:
By observing the conversion of [ ( 3 ) C ] ( L ) -arginine to [ ( 3 ) C ] ( L ) -citrulline, we found that
PGF stimulated
NOS activity in cultured LECs at 2 h ( P < 0.05 ) ... The overall findings indicate that bovine LECs are a target for PGF and that
PGF stimulates iNOS expression and
NOS activity in bovine LECs ...
Stimulation of the NO generating system and
NOS activity by
PGF may result in increasing local NO production followed by luteolysis
Novaro et al., Prostaglandins 1996
:
A competitive inhibitor of
NOS , L-NAME ( 600 and 1000 microM )
induced a decrease in PGE and
PGF2 alpha production in uterine tissue on day 5 of pregnancy
Perez Martinez et al., Prostaglandins Other Lipid Mediat 1998
:
In this paper, we evaluated the hypothesis that prostaglandin F2 alpha ( PGF2 alpha )
regulates NOS activity and we also investigated, by means of nitric oxide inhibitors ( N-monomethyl-L-arginine monoacetate, L-NMMA ) the role of endogenous NO on
PGF2 alpha induced contractions in rat oviduct