Gene interactions and pathways from curated databases and text-mining

◀ Back to TYK2

STAT5A — TYK2

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Lukashova et al., J Biol Chem 2001 : Activation of Tyk2 was followed by a time dependent 2-4-fold increase in the level of tyrosine phosphorylation of signal transducers and activators of transcription 1 ( STAT1 ), STAT2, and STAT3 and a sustained 2.5-fold increase in STAT5 tyrosine phosphorylation
Liu et al., Am J Respir Cell Mol Biol 2002 (Lung Neoplasms) : NRG-1 induced a rapid and transient increase in tyrosine phosphorylation of TYK2 and JAK3, but not JAK1 or JAK2, and induced STAT3 and STAT5 tyrosine phosphorylation
Versteeg et al., Circ Res 2004 : FVIIa induced STAT5 phosphorylation was dependent on functional G12/G13 class G proteins and Jak2 activity, but not Jak1 or Tyk2
Nakajima et al., Int J Hematol 2006 (Disease Models, Animal...) : We have previously shown that FLT3-ITD signals mainly through the signal transducer and activator of transcription 5 ( STAT5 ) pathway and have suggested the possible involvement of Tyk2 in STAT5 activation by FLT3-ITD
Shide et al., Leuk Res 2007 (Myeloproliferative Disorders...) : V678F Tyk2 augmented the transcriptional activity of Stat3 and Stat5