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PRKAG1 — TNFSF11
Text-mined interactions from Literome
Lee et al., Bone 2010
(Bone Resorption) :
STO-609, an inhibitor of CaMKK, completely blocked the
RANKL induced activation of
AMPK-a , but KN-93, an inhibitor of CaMK, did not ... siRNA mediated TAK1 knockdown also blocked
RANKL induced activation of
AMPK-a ...
AMPK negatively
regulates RANKL , possibly by acting through CaMKK and TAK1
Feng et al., Chin Med J (Engl) 2012
:
The
effect of
AMPK activation on
RANKL expression in hPDL cells was investigated by real-time PCR and Western blotting ... Suppression of
AMPK by Compound C
augmented RANKL expression, and AMPK activation by metformin significantly decreased RANKL expression in hPDL cells ... High glucose induced up-regulation of
RANKL could be due to decreased AMPK activity, and
AMPK activation may be
involved in regulating of RANKL expression in hPDL cells