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OPN1LW — SP1

Text-mined interactions from Literome

Sugawara et al., Hypertens Res 2003 (Arteriosclerosis...) : It is therefore speculated that : 1 ) PPAR-gamma phosphorylation by the MAP kinase pathway may attenuate PPAR-gamma mediated AT1R gene transcription suppression through the inhibition of PPAR-gamma activity ; and 2 ) CBP may enhance the activity of the remaining Sp1 on the -- 58/ -- 34 GC-box related element, resulting in a reduction in PPAR-gamma mediated AT1R gene transcription suppression
Webster et al., J Biol Chem 2013 : TNF, acting via NF-?B, did not change the levels of CREB, Sp1 , or Egr-1 binding to the Ga ( s ) promoter, but it induced a significant reduction in the level of CBP