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CASP14 — TCHP
Text-mined interactions from Literome
Cho et al., J Korean Med Sci 2001
:
When HL-60 cells, p53 null, were treated with etoposide, MDM2 was markedly decreased prior to
caspase-3 dependent retinoblastoma
tumor suppressor protein ( pRb ) and poly ( ADP- ribose ) polymerase ( PARP ) cleavages
Ollinger et al., Cell cycle (Georgetown, Tex.) 2007
:
The signaling cascades responsible for this action involved induction of p53, p27, hypophosphorylation of the retinoblastoma
tumor suppressor protein as well as
caspase activation
Kim et al., Mol Cell 2008
:
A
tumor suppressor protein , PHAPI,
enhances caspase-9 activation by promoting apoptosome formation through an unknown mechanism