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IFI27 — MAP2K1
Text-mined interactions from Literome
Hoshino et al., J Biol Chem 2001
(Neoplasms) :
Overexpression in RPMI-SE cells of either a kinase negative form of
MEK1 or wild-type MAP kinase phosphatase-3 also
induced up-regulation of
p27 ( Kip1 )
Zhang et al., J Biol Chem 2008
:
Parallel to cell death processes, overexpression of p21 or
p27 profoundly
enhanced DCA +
MEK1/2 inhibitor induced expression of ATG5 and GRP78/BiP and phosphorylation of PKR-like endoplasmic reticulum kinase ( PERK ) and eIF2alpha, and it increased the numbers of vesicles containing a transfected LC3-GFP construct
Ding et al., J Gastroenterol Hepatol 2008
(Helicobacter Infections...) :
MEK1/2 inhibition
increased p21,
p27 and cyclin E and JNK inhibition additionally increased cyclin D1 expression