Gene interactions and pathways from curated databases and text-mining

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ABL1 — IFI27

Text-mined interactions from Literome

Gesbert et al., J Biol Chem 2000 : Second, inhibition of BCR/ABL kinase activity with the Abl tyrosine kinase inhibitor STI571 rapidly increases p27 ( Kip1 ) levels
Pierce et al., Hematol J 2001 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : This enhanced BCR/ABL mediated growth inhibition occurred over a range of growth factor concentrations and was independent of changes in p21 ( Cip1 ) and p27 ( Kip ) levels
Chu et al., Leukemia 2010 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : Role of BCR-ABL-Y177 mediated p27kip1 phosphorylation and cytoplasmic localization in enhanced proliferation of chronic myeloid leukemia progenitors ... These studies show the importance of BCR-ABL-Y177-AKT mediated p27 phosphorylation in altered p27 localization and enhanced proliferation and expansion of primary CML progenitors